徐长亮
徐长亮，男，汉族，1981年09月出生。博士. 2012年毕业于中国药科大学，获中西医结合（基础）博士学位。（附照片）
近五年中目前主持有1项科研课题，国家自然科学基金青年基金课题1项。参与国家自然科学基金研究项目2项。发表和参与发表英文学术论文10篇，其中一作3篇，通讯作者2篇。 另有发表和参与发表中文学术论文8篇
研究方向
中药药理学。中药提取物中发现有效活性物质对肿瘤、神经退行性疾病以及肾脏疾病的药理活性研究以及机理探讨。
代表性科研成果
代表性学术论文
Cheng HB, Bo Y, Shen WX, Tan JN, Jia ZR, Xu CL, Li FR, Leonurine ameliorates kidney fibrosis via suppressing TGF-β and NF-κB signaling pathway in UUO mice; International Immunopharmacology. Accept（共通讯）
Cheng HB, Bo Y, Shen WX, Ren XG, Tan JN, Jia ZR, Xu CL, Longikaurin E induces apoptosis of pancreatic cancer cells via modulation of the p38 and PI3K/AKT pathways by ROS; Naunyn-Schmiedeberg's Archives of Pharmacology. Accept
Xu CL, Wang Q, Feng X, Bo Y, Effect of evodiagenine mediates photocytotoxicity on human breast cancer cells MDA-MB-231 through inhibition of PI3K/AKT/mTOR and activation of p38 pathways. Fitoterapia. 2014;99:292-9.
Xu CL, Qu R, Zhang J, Li LF, Ma SP, Neuroprotective effects of madecassoside in early stage of Parkinson's disease induced by MPTP in rats. Fitoterapia, 20(9):2013.
Li LF, Lu J, Li XM, Xu CL, Deng JM, Qu R, Ma SP, Antidepressant-like effect of magnolol on BDNF up-regulation and serotonergic system activity in unpredictable chronic mild stress treated rats, Phytother Res, 26(8):1189-94, 2012.
Li LF, Lu J, Li XM, Xu CL, Yang J, Qu R, Ma SP, Antidepressant-like effects of the saponins extracted from Chaihu-jia-longgu-muli-tang in a rat unpredictable chronic mild stress model, Fitoterapia, 83(1):93-103, 2012
Xu CL, Wang QZ, Sun LM, Li XM, Deng JM, Li LF, Zhang J, Xu R, Ma SP, Asiaticoside: attenuation of neurotoxicity induced by MPTP in a rat model of Parkinsonism via maintaining redox balance and up-regulating the ratio of Bcl-2/Bax, Pharmacol Biochem Behav, 100(3):413-8, 2012.
Li XM, Xu CL, Deng JM, Li LF, Ma SP, Qu R, Protective effect of Zhen-Wu-Tang (ZWT) through keeping DA stable and VMAT 2/DAT mRNA in balance in rats with striatal lesions induced by MPTP, J Ethnopharmacol, 12;134(3):768-74, 2011.
Ren TN, Wang JS, He YM, Xu CL, Wang SZ, Xi T, Effects of SMYD3 over-expression on cell cycle acceleration and cell proliferation in MDA-MB-231 human breast cancer cells, Med Oncol,28 Suppl 1:S91-8, 2011.
Li XM, Ma HB, Ma ZQ, Li LF, Xu CL, Qu R, Ma SP, Ameliorative and neuroprotective effect in MPTP model of Parkinson's disease by Zhen-Wu-Tang (ZWT), a traditional Chinese medicine, J Ethnopharmacol, 130(1):19-27, 2010.
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